Protein Molecular Weight Markers
ABclonal Technology EYA3 Rabbit pAb
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3 UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants.
ABclonal Technology HMGB3 Rabbit pAb
This gene encodes a member of a family of proteins containing one or more high mobility group DNA-binding motifs. The encoded protein plays an important role in maintaining stem cell populations, and may be aberrantly expressed in tumor cells. A mutation in this gene was associated with microphthalmia, syndromic 13. There are numerous pseudogenes of this gene on multiple chromosomes. Alternative splicing results in multiple transcript variants.
Echelon Biosciences Research Labs Select-HA Mega Ladder
The Select-HA Mega Ladder is a mixture of biotin-Select HA molecules of defined sizes for use as size standards in gel electrophoresis or other separation methods. This ladder covers a range from 2 megadalton to 8 megadalton. Select-HA™ is a hyaluronic acid (HA) preparation of uniform and narrow size distribution prepared by in vitro synthesis using recombinant Pasteurella multocida hyaluronan synthase. This item is non returnable
ABclonal Technology REC8 Rabbit pAb
Predicted to enable chromatin binding activity. Acts upstream of or within several processes, including gamete generation, seminiferous tubule development, and synaptonemal complex assembly. Located in kinetochore, lateral element, and male germ cell nucleus. Part of nuclear meiotic cohesin complex. Is expressed in several structures, including alimentary system, central nervous system, genitourinary system, respiratory system, and sensory organ. Orthologous to human REC8 (REC8 meiotic recombination protein).
ABclonal Technology LTBP3 Rabbit pAb
The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology TCHH Rabbit pAb
The protein encoded by this gene forms crosslinked complexes with itself and keratin intermediate filaments to provide mechanical strength to the hair follicle inner root sheath. The encoded protein also is important for structural integrity of the filiform papillae of the tongue. Defects in this gene are a cause of uncombable hair syndrome.
ABclonal Technology GABRG1 Rabbit pAb
The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. This gene is clustered with three other family members on chromosome 4.
ABclonal Technology IMPDH2 Rabbit pAb
This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5-monophosphate into xanthine-5-monophosphate, which is then converted into guanosine-5-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.
ABclonal Technology ZNF451 Rabbit pAb
Enables SUMO ligase activity and transcription corepressor activity. Involved in negative regulation of nitrogen compound metabolic process, negative regulation of transforming growth factor beta receptor signaling pathway, and protein sumoylation. Located in nucleus.
ABclonal Technology ATL2 Rabbit pAb
Enables identical protein binding activity. Involved in Golgi organization, endoplasmic reticulum tubular network membrane organization, and protein homooligomerization. Located in endoplasmic reticulum tubular network membrane. Is integral component of membrane.
ABclonal Technology CDK5RAP2 Rabbit pAb
This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimers disease. Alternative splicing results in multiple transcript variants.
ABclonal Technology UQCRH Rabbit mAb
Predicted to enable ubiquinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion.
ABclonal Technology COLEC12 Rabbit pAb
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.
Abcam Phosphate Assay Kit - PiColorLockTM.
Phosphate Assay Kit - PiColorLockTM.
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